| WARNING ! Zyban, Champix side-effects. Thursday, July 2, 2009 The U.S. Food and Drug Administration will require two smoking-cessation drugs, Champix and Zyban, to carry the agency's strongest safety warning over side-effects including depression and suicidal thoughts. The new requirement, "will highlight the risk of serious mental health events including changes in behavior, depressed mood, hostility, and suicidal thoughts when taking these drugs," the FDA said in a statement on its website. The antidepressant Wellbutrin, which has the same active ingredient as GlaxoSmithKline PLC's Zyban, already carries such a warning. The FDA said it is also requiring an additional study on Champix and Zyban to determine the extent of the side-effects. Pfizer Inc., which makes Champix, said it is still discussing the potential study design with the FDA. © The Canadian Press, 2009 | | |
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